Endocrine Abstracts

A 38–year-old female was diagnosed with right breast cancer cT2mN0M0G3 with positive BRCA+ gene mutation. The patient was treated with neoadjuvant chemotherapy plus one dose immune checkpoint inhibitor Pembrolizumab following bilateral radical mastectomy, extirpation of the right sentinel lymph nodes and bilateral reconstruction with an implant. Approximately one month after using Pembrolizumab the patient noticed extreme fatigue, decreased blood pressure, accelerated pul...

BackgroundCardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with increased risk of cardiovascular mortality. The significance of CAN has not been fully appreciated. Treatment of CAN includes physical activity.AimTo detect CAN status and measure the influence of physical activity on the autonomic nervous system using cardiovascular autonomic refl...

A 60–year-old male and 24–year-old female presented to the endocrinologist with hyperthyroidism of unknown cause. A 60-year-old male was admitted to the Department of Endocrinology with fatigue, dyspnoea, increased sweating, and anxiety. Hyperthyroidism was diagnosed with TSH < 0.0008 mIU/l [reference range: 0.3500 – 4.9400], FT4 – 4.03 ng/dl [reference range: 0.89 – 1.76] and FT3 – 12.96 [reference range: 2.3-4.2]. The patient had a...